Establishing Zhaoqing Medical Service System to Build the Guangdong, Hong Kong, and Macao Health Community

The construction of the Guangdong, Hong Kong, and Macao health community is not only an inherent requirement for the economic development and social progress of the Pearl River Delta region, but also an inevitable requirement for the realization of the healthy China strategy and the internationalization and modernization of medical and health care in the three cities. This article discusses answers to issues related to the Guangdong, Hong Kong, and Macao health community. It takes the construction of Zhaoqing medical service system in Guangdong Province as an entry point

Scatterer induced mode splitting in poly(dimethylsiloxane) coated microresonators

We investigate scatterer induced mode splitting in a composite microtoroidal resonator (Q ~ 10^6) fabricated by coating a silica microtoroid (Q ~ 10^7) with a thin poly(dimethylsiloxane) layer. We show that the two split modes in both coated and uncoated silica microtoroids respond in the same way to the changes in the environmental temperature. This provides a self-referencing scheme which is robust to temperature perturbations. Together with the versatile functionalities of polymer materials, mode splitting in polymer and polymer coated microresonators offers an attractive sensing platform that is robust to thermal noise.Comment: 9 pages, 3 figures, 15 reference

Pulmonary diseases induced by ambient ultrafine and engineered nanoparticles in twenty-first century.

Air pollution is a severe threat to public health globally, affecting everyone in developed and developing countries alike. Among different air pollutants, particulate matter (PM), particularly combustion-produced fine PM (PM2.5) has been shown to play a major role in inducing various adverse health effects. Strong associations have been demonstrated by epidemiological and toxicological studies between increases in PM2.5 concentrations and premature mortality, cardiopulmonary diseases, asthma and allergic sensitization, and lung cancer. The mechanisms of PM-induced toxicological effects are related to their size, chemical composition, lung clearance and retention, cellular oxidative stress responses and pro-inflammatory effects locally and systemically. Particles in the ultrafine range (<100 nm), although they have the highest number counts, surface area and organic chemical content, are often overlooked due to insufficient monitoring and risk assessment. Yet, ample studies have demonstrated that ambient ultrafine particles have higher toxic potential compared with PM2.5. In addition, the rapid development of nanotechnology, bringing ever-increasing production of nanomaterials, has raised concerns about the potential human exposure and health impacts. All these add to the complexity of PM-induced health effects that largely remains to be determined, and mechanistic understanding on the toxicological effects of ambient ultrafine particles and nanomaterials will be the focus of studies in the near future